Dual-Functional Liposomes with Carbonic Anhydrase IX Antibody and BR2 Peptide Modification Effectively Improve Intracellular Delivery of Cantharidin to Treat Orthotopic Hepatocellular Carcinoma Mice

Dual-Functional Liposomes with Carbonic Anhydrase IX Antibody and BR2 Peptide Modification Effectively Improve Intracellular Delivery of Cantharidin to Treat Orthotopic Hepatocellular Carcinoma Mice

Liposomal nanotechnology has a great potential to overcome the current major problems of chemotherapy. However, the lack of penetrability and targetability retards the successful delivery of liposomal carriers. Previously, we showed that BR2 peptide modification endowed cantharidin-loaded liposomes...

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Bibliographic Details
Main Authors: Xue Zhang, Congcong Lin, Waikei Chan, Kanglun Liu, Aiping Lu, Ge Lin, Rong Hu, Hongcan Shi, Hongqi Zhang, Zhijun Yang
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Molecules
Subjects:
hepatocellular carcinoma
dual-functionalized liposomes
carbonic anhydrase IX
BR2 peptide
cantharidin
Online Access:https://www.mdpi.com/1420-3049/24/18/3332

Internet

https://www.mdpi.com/1420-3049/24/18/3332

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