Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers

Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers

The main epigenetic features in aging are: reduced bulk levels of core histones, altered pattern of histone post-translational modifications, changes in the pattern of DNA methylation, replacement of canonical histones with histone variants, and altered expression of non-coding RNA. The identificati...

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Bibliographic Details
Main Authors: José Luis García-Giménez, Salvador Mena-Molla, Francisco José Tarazona-Santabalbina, Jose Viña, Mari Carmen Gomez-Cabrera, Federico V. Pallardó
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Environmental Research and Public Health
Subjects:
geriatric syndromes
healthy aging
exercise
histones
DNA methylation
non-coding RNA
Online Access:https://www.mdpi.com/1660-4601/18/4/1883

Internet

https://www.mdpi.com/1660-4601/18/4/1883

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