The Metabolism of Epoxyeicosatrienoic Acids by Soluble Epoxide Hydrolase Is Protective against the Development of Vascular Calcification

The Metabolism of Epoxyeicosatrienoic Acids by Soluble Epoxide Hydrolase Is Protective against the Development of Vascular Calcification

This study addressed the hypothesis that soluble epoxide hydrolase (sEH), which metabolizes endothelium-derived epoxyeicosatrienoic acids, plays a role in vascular calcification. The sEH inhibitor <i>trans</i>-4-(4-(3-adamantan-1-yl-ureido)-cyclohexyloxy)-benzoic acid (<i>t</i&g...

Full description

Bibliographic Details
Main Authors: Olivier Varennes, Romuald Mentaverri, Thomas Duflot, Gilles Kauffenstein, Thibaut Objois, Gaëlle Lenglet, Carine Avondo, Christophe Morisseau, Michel Brazier, Saïd Kamel, Isabelle Six, Jeremy Bellien
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
vascular calcification
soluble epoxide hydrolase
phosphatase
epoxyeicosatrienoic acids
Online Access:https://www.mdpi.com/1422-0067/21/12/4313

Internet

https://www.mdpi.com/1422-0067/21/12/4313

Similar Items