Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters

Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters

Abstract Background Bidirectional promoters (BPs) are prevalent in eukaryotic genomes. However, it is poorly understood how the cell integrates different epigenomic information, such as transcription factor (TF) binding and chromatin marks, to drive gene expression at BPs. Single-cell sequencing tec...

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Bibliographic Details
Main Authors: Fatemeh Behjati Ardakani, Kathrin Kattler, Karl Nordström, Nina Gasparoni, Gilles Gasparoni, Sarah Fuchs, Anupam Sinha, Matthias Barann, Peter Ebert, Jonas Fischer, Barbara Hutter, Gideon Zipprich, Charles D. Imbusch, Bärbel Felder, Jürgen Eils, Benedikt Brors, Thomas Lengauer, Thomas Manke, Philip Rosenstiel, Jörn Walter, Marcel H. Schulz
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Epigenetics & Chromatin
Subjects:
Bidirectional genes
Single-cell RNA-seq
Epigenetics
Online Access:http://link.springer.com/article/10.1186/s13072-018-0236-7

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http://link.springer.com/article/10.1186/s13072-018-0236-7

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