Effect of penehyclidine hydrochloride on -arrestin-1 expression in lipopolysaccharide-induced human pulmonary microvascular endothelial cells

β-arrestins are expressed proteins that were first described, and are well-known, as negative regulators of G protein-coupled receptor signaling. Penehyclidine hydrochloride (PHC) is a new anti-cholinergic drug that can inhibit biomembrane lipid peroxidation, and decrease cytokines and oxyradicals....

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Bibliographic Details
Main Authors: J. Zhan, F. Xiao, Z.Z. Zhang, Y.P. Wang, K. Chen, Y.L. Wang
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-12-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001201040&lng=en&tlng=en