Discrimination of Stereoisomers by Their Enantioselective Interactions with Chiral Cholesterol-Containing Membranes

Discrimination between enantiomers is an important subject in medicinal and biological chemistry because they exhibit markedly different bioactivity and toxicity. Although stereoisomers should vary in the mechanistic interactions with chiral targets, their discrimination associated with the mode of...

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Bibliographic Details
Main Authors: Hironori Tsuchiya, Maki Mizogami
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/23/1/49