A deletion in the N-myc downstream regulated gene 1 (NDRG1) gene in Greyhounds with polyneuropathy.

The polyneuropathy of juvenile Greyhound show dogs shows clinical similarities to the genetically heterogeneous Charcot-Marie-Tooth (CMT) disease in humans. The pedigrees containing affected dogs suggest monogenic autosomal recessive inheritance and all affected dogs trace back to a single male. Her...

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Main Authors: Cord Drögemüller, Doreen Becker, Barbara Kessler, Elisabeth Kemter, Jens Tetens, Konrad Jurina, Karin Hultin Jäderlund, Annette Flagstad, Michele Perloski, Kerstin Lindblad-Toh, Kaspar Matiasek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20582309/pdf/?tool=EBI