Amphiregulin induces interleukin-8 production and cell proliferation in lung epithelial cells through PI3K-Akt/ ERK pathways

Amphiregulin (AR), belongs to the epidermal growth factor (EGF) family, is able to induce a series of pathological and physiological responses by binding and activating epidermal growth factor receptor (EGFR). Interleukin-8 (IL-8) or CXCL8, a pro-inflammatory chemokine, has been suggested to be invo...

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Bibliographic Details
Main Authors: Fangfang Yang, Wei Xu, Yanli Pei
Format: Article
Language:English
Published: SAGE Publishing 2021-03-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/2058739221998202