CC chemokine ligand 2 upregulates the current density and expression of TRPV1 channels and Na<sub>v</sub>1.8 sodium channels in dorsal root ganglion neurons

CC chemokine ligand 2 upregulates the current density and expression of TRPV1 channels and Na<sub>v</sub>1.8 sodium channels in dorsal root ganglion neurons

<p>Abstract</p> <p>Background</p> <p>Inflammation or nerve injury-induced upregulation and release of chemokine CC chemokine ligand 2 (CCL2) within the dorsal root ganglion (DRG) is believed to enhance the activity of DRG nociceptive neurons and cause hyperalgesia. Tran...

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Bibliographic Details
Main Authors: Kao Der-Jang, Li Allen H, Chen Jin-Chung, Luo Ro-Sun, Chen Ying-Ling, Lu Juu-Chin, Wang Hung-Li
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Journal of Neuroinflammation
Subjects:
CC chemokine ligand 2
Dorsal root ganglion neurons
Transient receptor potential vanilloid receptor 1
Tetrodotoxin-resistant Na<sub>v</sub>1.8 sodium channel
Online Access:http://www.jneuroinflammation.com/content/9/1/189

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http://www.jneuroinflammation.com/content/9/1/189

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