The ISApl12 Dimer Circular Intermediate Participates in mcr-1 Transposition

The ISApl12 Dimer Circular Intermediate Participates in mcr-1 Transposition

Objectives: The mobile colistin resistance gene mcr-1 is a serious threat to global human and animal health. The composite transposon Tn6330 and its circular intermediate were proposed to be involved in the spread of mcr-1 but their roles remain poorly understood.Methods: To further explore the inte...

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Bibliographic Details
Main Authors: Yu-Zhang He, Xing-Ping Li, Yuan-Yuan Miao, Jun Lin, Ruan-Yang Sun, Xiao-Pei Wang, Ya-Ya Guo, Xiao-Ping Liao, Ya-Hong Liu, Youjun Feng, Jian Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Microbiology
Subjects:
transposition mechanism
mcr-1
circular intermediate
ISApl1
colistin resistance
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00015/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00015/full

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