Aggregation-Induced Emission: Lighting Up hERG Potassium Channel

Based on the scaffold of astemizole and E-4031, four AIE light-up probes (L1–L4) for Human Ether-a-go-go-Related Gene (hERG) potassium channel were developed herein using AIE fluorogen(TPE). These probes showing advantages such as low background interference, superior photostability, acceptable cell...

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Bibliographic Details
Main Authors: Xiaomeng Zhang, Tingting Liu, Qi Li, Minyong Li, Lupei Du
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00054/full