Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice.

1-Methylnicotinamide (MNA), which was initially considered to be a biologically inactive endogenous metabolite of nicotinamide, has emerged as an anti-thrombotic and anti-inflammatory agent with the capacity to release prostacyclin (PGI2). In the present study, we characterized the effects of MNA on...

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Main Authors: Kamil Przyborowski, Marta Wojewoda, Barbara Sitek, Agnieszka Zakrzewska, Agnieszka Kij, Krystyna Wandzel, Jerzy Andrzej Zoladz, Stefan Chlopicki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4482656?pdf=render