Estimating Copy-Number Proportions: The Comeback of Sanger Sequencing

Estimating Copy-Number Proportions: The Comeback of Sanger Sequencing

Determination of the relative copy numbers of mixed molecular species in nucleic acid samples is often the objective of biological experiments, including Single-Nucleotide Polymorphism (SNP), indel and gene copy-number characterization, and quantification of CRISPR-Cas9 base editing, cytosine methyl...

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Bibliographic Details
Main Author: Eyal Seroussi
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Genes
Subjects:
dye-terminator DNA sequencing
SNP
CNV
CpG
bisulfite sequencing
base editor
Online Access:https://www.mdpi.com/2073-4425/12/2/283

Internet

https://www.mdpi.com/2073-4425/12/2/283

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