Colestilan decreases weight gain by enhanced NEFA incorporation in biliary lipids and fecal lipid excretion[S]

Colestilan decreases weight gain by enhanced NEFA incorporation in biliary lipids and fecal lipid excretion[S]

Bile acid sequestrants (BASs) are cholesterol-lowering drugs that also affect hyperglycemia. The mechanism by which BASs exert these and other metabolic effects beyond cholesterol lowering remains poorly understood. The present study aimed to investigate the effects of a BAS, colestilan, on body wei...

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Bibliographic Details
Main Authors: Kanami Sugimoto-Kawabata, Hiroshi Shimada, Kaoru Sakai, Kazuo Suzuki, Thomas Kelder, Elsbet J. Pieterman, Louis H. Cohen, Louis M. Havekes, Hans M. Princen, Anita M. van den Hoek
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Journal of Lipid Research
Subjects:
adipose tissue
bile acid sequestrant
hyperinsulinemic-euglycemic clamp
insulin sensitivity
nonesterified fatty acid
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520421649

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http://www.sciencedirect.com/science/article/pii/S0022227520421649

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