Leptin Elicits In Vivo Eosinophil Migration and Activation: Key Role of Mast Cell-Derived PGD2

Leptin Elicits In Vivo Eosinophil Migration and Activation: Key Role of Mast Cell-Derived PGD2

Eosinophils are key regulators of adipose tissue homeostasis, thus characterization of adipose tissue-related molecular factors capable of regulating eosinophil activity is of great interest. Leptin is known to directly activate eosinophils in vitro, but leptin ability of inducing in vivo eosinophil...

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Bibliographic Details
Main Authors: Natália R. T. Amorim, Glaucia Souza-Almeida, Tatiana Luna-Gomes, Patricia T. Bozza, Claudio Canetti, Bruno L. Diaz, Clarissa M. Maya-Monteiro, Christianne Bandeira-Melo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Endocrinology
Subjects:
eosinophils
mast cells
lipid droplets
leptin
prostaglandin D2
leukotriene C4
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.572113/full

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https://www.frontiersin.org/article/10.3389/fendo.2020.572113/full

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