Thermal Activation of Thin Filaments in Striated Muscle

In skeletal and cardiac muscles, contraction is triggered by an increase in the intracellular Ca2+ concentration. During Ca2+ transients, Ca2+-binding to troponin C shifts the “on–off” equilibrium of the thin filament state toward the “on” sate, promoting actomyosin interaction. Likewise, recent stu...

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Bibliographic Details
Main Authors: Shuya Ishii, Kotaro Oyama, Seine A. Shintani, Fuyu Kobirumaki-Shimozawa, Shin’ichi Ishiwata, Norio Fukuda
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00278/full