Thermal Activation of Thin Filaments in Striated Muscle
In skeletal and cardiac muscles, contraction is triggered by an increase in the intracellular Ca2+ concentration. During Ca2+ transients, Ca2+-binding to troponin C shifts the “on–off” equilibrium of the thin filament state toward the “on” sate, promoting actomyosin interaction. Likewise, recent stu...
Main Authors: | Shuya Ishii, Kotaro Oyama, Seine A. Shintani, Fuyu Kobirumaki-Shimozawa, Shin’ichi Ishiwata, Norio Fukuda |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-04-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fphys.2020.00278/full |
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