Role of hydrogen sulfide in early blood-brain barrier disruption following transient focal cerebral ischemia.

We determined the role of endogenous hydrogen sulfide (H2S) in cerebral vasodilation/hyperemia and early BBB disruption following ischemic stroke. A cranial window was prepared over the left frontal, parietal and temporal cortex in mice. Transient focal cerebral Ischemia was induced by directly liga...

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Bibliographic Details
Main Authors: Zheng Jiang, Chun Li, Morganne L Manuel, Shuai Yuan, Christopher G Kevil, Kimberly D McCarter, Wei Lu, Hong Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4335059?pdf=render