Inhibition of endoplasmic reticulum stress improves mouse embryo development.

X-box binding protein-1 (XBP-1) is an important regulator of a subset of genes during endoplasmic reticulum (ER) stress. In the current study, we analyzed endogenous XBP-1 expression and localization, with a view to determining the effects of ER stress on the developmental competency of preimplantat...

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Bibliographic Details
Main Authors: Jin Yu Zhang, Yun Fei Diao, Hong Rye Kim, Dong Il Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22808162/?tool=EBI