Synthesis and Spectral Identification of Three Schiff Bases with a 2-(Piperazin-1-yl)-<i>N</i>-(thiophen-2-yl methylene)ethanamine Moiety Acting as Novel Pancreatic Lipase Inhibitors: Thermal, DFT, Antioxidant, Antibacterial, and Molecular Docking Investigations

Synthesis and Spectral Identification of Three Schiff Bases with a 2-(Piperazin-1-yl)-<i>N</i>-(thiophen-2-yl methylene)ethanamine Moiety Acting as Novel Pancreatic Lipase Inhibitors: Thermal, DFT, Antioxidant, Antibacterial, and Molecular Docking Investigations

Three new tetradentate NNNS Schiff bases (<b>L1</b>–<b>L3</b>) derived from 2-(piperidin-4-yl)ethanamine were prepared in high yields. UV–Visible and FTIR spectroscopy were used to monitor the dehydration reaction between 2-(piperidin-4-yl)ethanamine and the corresponding ald...

Full description

Bibliographic Details
Main Authors: Ismail Warad, Oraib Ali, Anas Al Ali, Nidal Amin Jaradat, Fatima Hussein, Lubna Abdallah, Nabil Al-Zaqri, Ali Alsalme, Fahad A. Alharthi
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Molecules
Subjects:
Schiff base
antimicrobial
DFT
pancreatic lipase inhibitors
Online Access:https://www.mdpi.com/1420-3049/25/9/2253

Internet

https://www.mdpi.com/1420-3049/25/9/2253

Similar Items