The Vibrio cholerae SpeG Spermidine/Spermine N-Acetyltransferase Allosteric Loop and β6-β7 Structural Elements Are Critical for Kinetic Activity

The Vibrio cholerae SpeG Spermidine/Spermine N-Acetyltransferase Allosteric Loop and β6-β7 Structural Elements Are Critical for Kinetic Activity

Polyamines regulate many important biological processes including gene expression, intracellular signaling, and biofilm formation. Their intracellular concentrations are tightly regulated by polyamine transport systems and biosynthetic and catabolic pathways. Spermidine/spermine N-acetyltransferases...

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Bibliographic Details
Main Authors: Van Thi Bich Le, Sofiya Tsimbalyuk, Ee Qi Lim, Allan Solis, Darwin Gawat, Paloma Boeck, Ee Qing Lim, Rosselini Renolo, Jade K. Forwood, Misty L. Kuhn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
Gcn5-related N-acetyltransferase
spermidine/spermine N-acetyltransferase
polyamine
allosteric regulation
acetylation
spermidine
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.645768/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.645768/full

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