Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma

<p>Abstract</p> <p>Background</p> <p>The continuous exposure of esophageal epithelium to refluxate may induce ectopic expression of bile-responsive genes and contribute to the development of Barrett's esophagus (BE) and esophageal adenocarcinoma. In normal physiolo...

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Bibliographic Details
Main Authors: Kusters Johannes G, Siersema Peter D, van Dekken Herman, Pot Raymond GJ, Moons Leon MG, Capello Astrid, Menke Vivianda, van de Winkel Anouk, van der Laan Luc JW, Kuipers Ernst J
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/11/108