Streptozotocin-Induced Diabetes Models: Pathophysiological Mechanisms and Fetal Outcomes

Glucose homeostasis is controlled by endocrine pancreatic cells, and any pancreatic disturbance can result in diabetes. Because 8% to 12% of diabetic pregnant women present with malformed fetuses, there is great interest in understanding the etiology, pathophysiological mechanisms, and treatment of...

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Main Authors: D. C. Damasceno, A. O. Netto, I. L. Iessi, F. Q. Gallego, S. B. Corvino, B. Dallaqua, Y. K. Sinzato, A. Bueno, I. M. P. Calderon, M. V. C. Rudge
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/819065