Co-expression of α9β1 integrin and VEGF-D confers lymphatic metastatic ability to a human breast cancer cell line MDA-MB-468LN.

INTRODUCTION AND OBJECTIVES: Lymphatic metastasis is a common occurrence in human breast cancer, mechanisms remaining poorly understood. MDA-MB-468LN (468LN), a variant of the MDA-MB-468GFP (468GFP) human breast cancer cell line, produces extensive lymphatic metastasis in nude mice. 468LN cells diff...

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Bibliographic Details
Main Authors: Mousumi Majumder, Elena Tutunea-Fatan, Xiping Xin, Mauricio Rodriguez-Torres, Jose Torres-Garcia, Ryan Wiebe, Alexander V Timoshenko, Rabindra N Bhattacharjee, Ann F Chambers, Peeyush K Lala
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335831?pdf=render