mTOR Regulation of Metabolism in Hematologic Malignancies

Neoplastic cells rewire their metabolism, acquiring a selective advantage over normal cells and a protection from therapeutic agents. The mammalian Target of Rapamycin (mTOR) is a serine/threonine kinase involved in a variety of cellular activities, including the control of metabolic processes. mTOR...

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Bibliographic Details
Main Authors: Simone Mirabilii, Maria Rosaria Ricciardi, Agostino Tafuri
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/2/404