Prolonged Normothermic Ex Vivo Kidney Perfusion Is Superior to Cold Nonoxygenated and Oxygenated Machine Perfusion for the Preservation of DCD Porcine Kidney Grafts

Background. The increased usage of marginal grafts has triggered interest in perfused kidney preservation to minimize graft injury. We used a donation after circulatory death (DCD) porcine kidney autotransplantation model to compare 3 of the most frequently used ex vivo kidney perfusion techniques:...

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Main Authors: Laura I. Mazilescu, MD, Peter Urbanellis, MD, MSc, Moritz J. Kaths, MD, MSc, Sujani Ganesh, MSc, Toru Goto, MD, Yuki Noguchi, MD, PhD, Rohan John, MD, Ana Konvalinka, MD, PhD, Istvan Mucsi, MD, PhD, Anand Ghanekar, MD, PhD, Darius J. Bagli, MD, MSc, Julie Turgeon, PhD, Annie Karakeusian Rimbaud, BSc, Marie-Josée Hébert, MD, Mélanie Dieudé, PhD, Isabelle Alleys, PhD, Etienne Dore, MSc, Eric Boilard, PhD, Herman S. Overkleeft, PhD, Lianne I. Willems, PhD, Lisa A. Robinson, MD, Markus Selzner, MD
Format: Article
Language:English
Published: Wolters Kluwer 2021-10-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001218