Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells

Pioglitazone Attenuates Palmitate-Induced Inflammation and Endoplasmic Reticulum Stress in Pancreatic β-Cells

BackgroundThe nuclear receptor peroxisome proliferator-activator gamma (PPARγ) is a useful therapeutic target for obesity and diabetes, but its role in protecting β-cell function and viability is unclear.MethodsTo identify the potential functions of PPARγ in β-cells, we treated mouse insulinoma 6 (M...

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Bibliographic Details
Main Authors: Seok-Woo Hong, Jinmi Lee, Jung Hwan Cho, Hyemi Kwon, Se Eun Park, Eun-Jung Rhee, Cheol-Young Park, Ki-Won Oh, Sung-Woo Park, Won-Young Lee
Format: Article
Language:English
Published: Academya Publishing Co. 2018-03-01
Series:Endocrinology and Metabolism
Subjects:
Pioglitazone
Insulin-secreting cells
Glucolipotoxicity
Inflammation
Endoplasmic reticulum stress
Online Access:https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-33-105.pdf

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https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-33-105.pdf

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