HDAC Inhibition Increases HLA Class I Expression in Uveal Melanoma

HDAC Inhibition Increases HLA Class I Expression in Uveal Melanoma

The treatment of uveal melanoma (UM) metastases or adjuvant treatment may imply immunological approaches or chemotherapy. It is to date unknown how epigenetic modifiers affect the expression of immunologically relevant targets, such as the HLA Class I antigens, in UM. We investigated the expression...

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Bibliographic Details
Main Authors: Zahra Souri, Aart G. Jochemsen, Mieke Versluis, Annemijn P.A. Wierenga, Fariba Nemati, Pieter A. van der Velden, Wilma G.M. Kroes, Robert M. Verdijk, Gregorius P.M. Luyten, Martine J. Jager
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
eye diseases
uveal melanoma
oncology
HLA
HDAC
immunology
Online Access:https://www.mdpi.com/2072-6694/12/12/3690

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https://www.mdpi.com/2072-6694/12/12/3690

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