Serum syndecan-1 reflects organ dysfunction in critically ill patients

Abstract Syndecan-1 (SDC-1) is found in the endothelial glycocalyx and shed into the blood during systemic inflammatory conditions. We investigated organ dysfunction associated with changing serum SDC-1 levels for early detection of organ dysfunction in critically ill patients. To evaluate the effec...

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Bibliographic Details
Main Authors: Keiko Suzuki, Hideshi Okada, Kazuyuki Sumi, Hiroyuki Tomita, Ryo Kobayashi, Takuma Ishihara, Yoshinori Kakino, Kodai Suzuki, Naomasa Yoshiyama, Ryu Yasuda, Yuichiro Kitagawa, Tetsuya Fukuta, Takahito Miyake, Haruka Okamoto, Tomoaki Doi, Takahiro Yoshida, Shozo Yoshida, Shinji Ogura, Akio Suzuki
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88303-7