Transposon mutagenesis as an approach to improved understanding of Borrelia pathogenesis and biology

Transposon insertion provides a method for near-random mutation of bacterial genomes, and has been utilized extensively for the study of bacterial pathogenesis and biology. This approach is particularly useful for organisms that are relatively refractory to genetic manipulation, including Lyme dise...

Full description

Bibliographic Details
Main Authors: Tao eLin, Erin B Troy, Linden T Hu, Lihui eGao, Steven J Norris
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00063/full