Promising effects of xanthine oxidase inhibition by allopurinol on autonomic heart regulation estimated by heart rate variability (HRV) analysis in rats exposed to hypoxia and hyperoxia.

Promising effects of xanthine oxidase inhibition by allopurinol on autonomic heart regulation estimated by heart rate variability (HRV) analysis in rats exposed to hypoxia and hyperoxia.

It has long been suggested that reactive oxygen species (ROS) play a role in oxygen sensing via peripheral chemoreceptors, which would imply their involvement in chemoreflex activation and autonomic regulation of heart rate. We hypothesize that antioxidant affect neurogenic cardiovascular regulation...

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Bibliographic Details
Main Authors: Stanisław Zajączkowski, Wiesław Ziółkowski, Piotr Badtke, Miłosz A Zajączkowski, Damian J Flis, Adam Figarski, Maria Smolińska-Bylańska, Tomasz H Wierzba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5809044?pdf=render

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http://europepmc.org/articles/PMC5809044?pdf=render

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