Therapeutic Effect of Repurposed Temsirolimus in Lung Adenocarcinoma Model

Therapeutic Effect of Repurposed Temsirolimus in Lung Adenocarcinoma Model

Lung cancer is one of the major cause of cancer-related deaths worldwide. The poor prognosis and resistance to both radiation and chemotherapy urged the development of potential targets for lung cancer treatment. In this study, using a network-based cellular signature bioinformatics approach, we rep...

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Bibliographic Details
Main Authors: Hsuen-Wen Chang, Min-Ju Wu, Zih-Miao Lin, Chueh-Yi Wang, Shu-Yun Cheng, Yen-Kuang Lin, Yen-Hung Chow, Hui-Ju Ch’ang, Vincent H. S. Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
mTOR inhibitor
drug repositioning
temsirolimus
lung adenocarcinoma
chemotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00778/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00778/full

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