Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression

Heme Oxygenase 1 (HMOX1) is an enzyme that catalyzes the reaction that degrades the heme group contained in several important proteins, such as hemoglobin, myoglobin, and cytochrome p450. The enzymatic reaction catalyzed by HMOX1 generates Fe2+, biliverdin and CO. It has been shown that HMOX1 activi...

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Main Authors: Valentina P. Sebastián, Geraldyne A. Salazar, Irenice Coronado-Arrázola, Bárbara M. Schultz, Omar P. Vallejos, Loni Berkowitz, Manuel M. Álvarez-Lobos, Claudia A. Riedel, Alexis M. Kalergis, Susan M. Bueno
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01956/full