Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production.

Mycolic acid modification by the mmaA4 gene of M. tuberculosis modulates IL-12 production.

Mycobacterium tuberculosis has evolved many strategies to evade elimination by the host immune system, including the selective repression of macrophage IL-12p40 production. To identify the M. tuberculosis genes responsible for this aspect of immune evasion, we used a macrophage cell line expressing...

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Bibliographic Details
Main Authors: Dee N Dao, Kari Sweeney, Tsungda Hsu, Sudagar S Gurcha, Ivan P Nascimento, Dan Roshevsky, Gurdyal S Besra, John Chan, Steven A Porcelli, William R Jacobs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18535659/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18535659/?tool=EBI

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