On the optimistic performance evaluation of newly introduced bioinformatic methods

Abstract Most research articles presenting new data analysis methods claim that “the new method performs better than existing methods,” but the veracity of such statements is questionable. Our manuscript discusses and illustrates consequences of the optimistic bias occurring during the evaluation of...

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Bibliographic Details
Main Authors: Stefan Buchka, Alexander Hapfelmeier, Paul P. Gardner, Rory Wilson, Anne-Laure Boulesteix
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02365-4