Inhibitory Effect of Avenanthramides (Avn) on Tyrosinase Activity and Melanogenesis in α-MSH-Activated SK-MEL-2 Cells: In Vitro and In Silico Analysis

Inhibitory Effect of Avenanthramides (Avn) on Tyrosinase Activity and Melanogenesis in α-MSH-Activated SK-MEL-2 Cells: In Vitro and In Silico Analysis

Melanin causes melasma, freckles, age spots, and chloasma. Anti-melanogenic agents can prevent disease-related hyperpigmentation. In the present study, the dose-dependent tyrosinase inhibitory activity of Avenanthramide (Avn)-A-B-C was demonstrated, and 100 µM Avn-A-B-C produced the strongest compet...

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Bibliographic Details
Main Authors: Jun-Young Park, Hyun-Ju Choi, Tamina Park, Moon-Jo Lee, Hak-Seong Lim, Woong-Suk Yang, Cher-Won Hwang, Daeui Park, Cheorl-Ho Kim
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
Avn-A-B-C
anti-melanogenesis
docking simulation
Online Access:https://www.mdpi.com/1422-0067/22/15/7814

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https://www.mdpi.com/1422-0067/22/15/7814

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