Clinical significance of CD8+ T cell immunoreceptor with Ig and ITIM domains+ in locally advanced gastric cancer treated with SOX regimen after D2 gastrectomy

Clinical significance of CD8+ T cell immunoreceptor with Ig and ITIM domains+ in locally advanced gastric cancer treated with SOX regimen after D2 gastrectomy

Gastric cancer (GC) development and progression is significantly associated with tumour immune escape. T cell immunoreceptor with Ig and ITIM domains (TIGIT) inhibits T-cell responses and is associated with human cancers and T cell exhaustion phenotypes, but its role in cancers remains unclear. TIGI...

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Bibliographic Details
Main Authors: Weiwei Tang, Xiongxiong Pan, Di Han, Dawei Rong, Minghui Zhang, Lulu Yang, Jie Ying, Hua Guan, Ziyi Chen, Xuehao Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-06-01
Series:OncoImmunology
Subjects:
gastric cancer
tigit
sox regimen
immune checkpoint
biomarker
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1593807

Internet

http://dx.doi.org/10.1080/2162402X.2019.1593807

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