Therapeutic Efficacy of Excretory-Secretory Products of Trichinella spiralis Adult Worms on Sepsis-Induced Acute Lung Injury in a Mouse Model

Therapeutic Efficacy of Excretory-Secretory Products of Trichinella spiralis Adult Worms on Sepsis-Induced Acute Lung Injury in a Mouse Model

Acute lung injury (ALI) is a common complication of systemic inflammation or sepsis with high morbidity and mortality. Although many studies have confirmed that helminth-derived proteins had strong immunomodulatory functions and could be used to treat inflammatory diseases, there is no report on the...

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Bibliographic Details
Main Authors: Huihui Li, Dapeng Qiu, Huijuan Yang, Yuan Yuan, Lingqin Wu, Liang Chu, Bin Zhan, Xiaoli Wang, Yan Sun, Wei Xu, Xiaodi Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
excretory-secretory products
Trichinella spiralis
sepsis
acute lung injury
cecal ligation and puncture
immunomodulation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.653843/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.653843/full

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