Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria
Abstract Oxidative stress and mitochondrial dysfunction have been associated with metabolic and age-related diseases. Thus, the prevention of mitochondrial oxidative damage is nowadays a recognized pharmacological strategy to delay disease progression. Epidemiological studies suggested an associatio...
Main Authors: | José Teixeira, Catarina Oliveira, Ricardo Amorim, Fernando Cagide, Jorge Garrido, José A. Ribeiro, Carlos M. Pereira, António F. Silva, Paula B. Andrade, Paulo J. Oliveira, Fernanda Borges |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-07272-y |
Similar Items
-
Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors
by: Catarina Oliveira, et al.
Published: (2018-04-01) -
Discovery of a new mitochondria permeability transition pore (mPTP) inhibitor based on gallic acid
by: José Teixeira, et al.
Published: (2018-01-01) -
Corynebacterium glutamicum as platform for the production of hydroxybenzoic acids
by: Nicolai Kallscheuer, et al.
Published: (2018-05-01) -
Antioxidant activity and calcium binding of isomeric hydroxybenzoates
by: Zichen Zhao, et al.
Published: (2018-04-01) -
Targeting dietary antioxidants to mitochondria: regulating mitochondrial radical production and redox signaling to improve human health
by: José Carlos Santos Teixeira
Published: (2019)