High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.

High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.

Breakdown of B cell tolerance is a cardinal feature of systemic lupus erythematosus (SLE). Increased numbers of autoreactive mature naïve B cells have been described in SLE patients and autoantibodies have been shown to arise from autoreactive and non-autoreactive precursors. How these defects, in t...

Full description

Bibliographic Details
Main Authors: Kaval Kaur, Nai-Ying Zheng, Kenneth Smith, Min Huang, Lie Li, Noel T Pauli, Carole J Henry Dunand, Jane-Hwei Lee, Michael Morrissey, Yixuan Wu, Michelle L Joachims, Melissa E Munroe, Denise Lau, Xinyan Qu, Florian Krammer, Jens Wrammert, Peter Palese, Rafi Ahmed, Judith A James, Patrick C Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4423960?pdf=render

Internet

http://europepmc.org/articles/PMC4423960?pdf=render

Similar Items