edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens [v2; ref status: indexed, http://f1000r.es/4kw]

edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens [v2; ref status: indexed, http://f1000r.es/4kw]

Pooled library sequencing screens that perturb gene function in a high-throughput manner are becoming increasingly popular in functional genomics research. Irrespective of the mechanism by which loss of function is achieved, via either RNA interference using short hairpin RNAs (shRNAs) or genetic mu...

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Bibliographic Details
Main Authors: Zhiyin Dai, Julie M. Sheridan, Linden J. Gearing, Darcy L. Moore, Shian Su, Sam Wormald, Stephen Wilcox, Liam O'Connor, Ross A. Dickins, Marnie E. Blewitt, Matthew E. Ritchie
Format: Article
Language:English
Published: F1000 Research Ltd 2014-10-01
Series:F1000Research
Subjects:
Bioinformatics
Online Access:http://f1000research.com/articles/3-95/v2

Internet

http://f1000research.com/articles/3-95/v2

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