Pathobiological and Genomic Characterization of a Cold-Adapted Infectious Bronchitis Virus (BP-caKII)

Pathobiological and Genomic Characterization of a Cold-Adapted Infectious Bronchitis Virus (BP-caKII)

We established a cold-adapted infectious bronchitis virus (BP-caKII) by passaging a field virus through specific pathogen-free embryonated eggs 20 times at 32 °C. We characterized its growth kinetics and pathogenicity in embryonated eggs, and its tropism and persistence in different tissues...

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Bibliographic Details
Main Authors: Seung-Min Hong, Se-Hee An, Chung-Young Lee, Chang-Seon Song, Kang-Seuk Choi, Jae-Hong Kim, Hyuk-Joon Kwon
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Viruses
Subjects:
infectious bronchitis virus
cold adaptation
comparative genomics
premature reproductive tract pathogenicity model
persistent infection
Online Access:https://www.mdpi.com/1999-4915/10/11/652

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https://www.mdpi.com/1999-4915/10/11/652

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