Unique Role of Histone Methyltransferase PRDM8 in the Tumorigenesis of Virus-negative Merkel Cell Carcinoma

Merkel cell carcinoma (MCC) is a deadly skin cancer, and about 80% of its cases have been shown to harbor integrated Merkel polyomavirus in the tumor cell genome. Viral oncoproteins expressed in the tumor cells are considered as the oncogenic factors of these virus-positive Merkel cell carcinoma (VP...

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Bibliographic Details
Main Authors: Elias Orouji, Wiebke K. Peitsch, Azadeh Orouji, Roland Houben, Jochen Utikal
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/4/1057