Network excitability in a model of chronic temporal lobe epilepsy critically depends on SK channel-mediated AHP currents
Hippocampal CA1 pyramidal neurons generate an after-hyperpolarization (AHP) whose medium component is thought to be generated by small-conductance Ca2+-activated K+ channels (SK channels). Neuronal excitability is increased in epilepsy, and the AHP in turn is fundamentally involved in regulation of...
|Main Authors:||, , , , ,|
|Series:||Neurobiology of Disease|