Prioritizing antiviral drugs against SARS-CoV-2 by integrating viral complete genome sequences and drug chemical structures

Abstract The outbreak of a novel febrile respiratory disease called COVID-19, caused by a newfound coronavirus SARS-CoV-2, has brought a worldwide attention. Prioritizing approved drugs is critical for quick clinical trials against COVID-19. In this study, we first manually curated three Virus-Drug...

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Bibliographic Details
Main Authors: Lihong Peng, Ling Shen, Junlin Xu, Xiongfei Tian, Fuxing Liu, Juanjuan Wang, Geng Tian, Jialiang Yang, Liqian Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83737-5