Proteomic biomarkers for acute interstitial lung disease in gefitinib-treated Japanese lung cancer patients.

Proteomic biomarkers for acute interstitial lung disease in gefitinib-treated Japanese lung cancer patients.

Interstitial lung disease (ILD) events have been reported in Japanese non-small-cell lung cancer (NSCLC) patients receiving EGFR tyrosine kinase inhibitors. We investigated proteomic biomarkers for mechanistic insights and improved prediction of ILD. Blood plasma was collected from 43 gefitinib-trea...

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Bibliographic Details
Main Authors: Fredrik Nyberg, Atsushi Ogiwara, Chris G Harbron, Takao Kawakami, Keiko Nagasaka, Sachiko Takami, Kazuya Wada, Hsiao-Kun Tu, Makiko Otsuji, Yutaka Kyono, Tae Dobashi, Yasuhiko Komatsu, Makoto Kihara, Shingo Akimoto, Ian S Peers, Marie C South, Tim Higenbottam, Masahiro Fukuoka, Koichiro Nakata, Yuichiro Ohe, Shoji Kudoh, Ib Groth Clausen, Toshihide Nishimura, György Marko-Varga, Harubumi Kato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3140475?pdf=render

Internet

http://europepmc.org/articles/PMC3140475?pdf=render

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