Randomized Phase II Study with Cetuximab in Combination with 5-FU and Cisplatin or Carboplatin vs. Cetuximab in Combination with Paclitaxel and Carboplatin for Treatment of Patients with Relapsed or Metastatic Squamous Cell Carcinoma of the Head and Neck (CETMET Trial)

Randomized Phase II Study with Cetuximab in Combination with 5-FU and Cisplatin or Carboplatin vs. Cetuximab in Combination with Paclitaxel and Carboplatin for Treatment of Patients with Relapsed or Metastatic Squamous Cell Carcinoma of the Head and Neck (CETMET Trial)

Background: Platinum-based chemotherapy with cetuximab is the standard of care for relapsed or metastatic squamous cell carcinoma of the head and neck (SCCHN). The aim of this trial was to investigate whether cetuximab and paclitaxel/carboplatin can achieve similar progression-free survival (PFS) wi...

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Bibliographic Details
Main Authors: Georgios Tsakonas, Lena Specht, Claus Andrup Kristensen, Maria Herlestam Calero Moreno, Hedda Haugen Cange, Karin Soderstrom, Signe Friesland
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
relapsed/metastatic SCCHN
cetuximab
carboplatin/paclitaxel
cisplatin/5-FU
first-line therapy
Online Access:https://www.mdpi.com/2072-6694/12/11/3110

Internet

https://www.mdpi.com/2072-6694/12/11/3110

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