Bile acid recognition by the Clostridium difficile germinant receptor, CspC, is important for establishing infection.
Clostridium difficile spores must germinate in vivo to become actively growing bacteria in order to produce the toxins that are necessary for disease. C. difficile spores germinate in vitro in response to certain bile acids and glycine. In other sporulating bacteria, proteins embedded within the inn...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-05-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC3649964?pdf=render |