Pharmacogenetics of HMG-CoA reductase inhibitors (statins): perspectives of individualized, genotype-based therapy

Statins’ efficacy in coronary heart disease treatment is well known, but their effectiveness is a subject to substantial individual differences. Partially, it is explained by genetic polymorphism. Individual pharmacological response to statins might depend on genetic polymorphism of the proteins det...

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Bibliographic Details
Main Authors: D. A. Sychev, A. V. Semenov, G. V. Ramenskaya, I. V. Ignatyev, S. V. Paukov, V. G. Kukes
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2006-02-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1120