HIF-1α is Overexpressed in Odontogenic Keratocyst Suggesting Activation of HIF-1α and NOTCH1 Signaling Pathways

HIF-1α is Overexpressed in Odontogenic Keratocyst Suggesting Activation of HIF-1α and NOTCH1 Signaling Pathways

<b>Background: </b>The odontogenic keratocyst (OKC) is an odontogenic cyst that shows aggressive and intriguing biological behavior. It is suggested that a hypoxic environment occurs in OKC, which led us to investigate the immunoexpression and location of hypoxia-inducible factor 1-alpha...

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Bibliographic Details
Main Authors: Natacha Malu Miranda da Costa, Caio Tadashi Saab Abe, Geovanni Pereira Mitre, Ricardo Alves Mesquita, Maria Sueli da Silva Kataoka, André Luis Ribeiro Ribeiro, Ruy Gastaldoni Jaeger, Sérgio de Melo Alves-Júnior, Andrew Mark Smith, João de Jesus Viana Pinheiro
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Cells
Subjects:
odontogenic keratocyst
HIF-1α
hypoxia
oxygen
Online Access:https://www.mdpi.com/2073-4409/8/7/731

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https://www.mdpi.com/2073-4409/8/7/731

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